| Basic Chemistry | Craft an item |
| Gunsmith | Improve a weapon |
| Get Organized | Expand your inventory |
| Power Stones | Place all jewels in the clock tower monument |
| Electric Slide | Gather the fuses in the warehouse within 5 minutes |
| Hello, Charlie! | Destroy a Charlie Doll |
| Two For One Deal | Defeat two enemies with a single shot |
| Bookworm | Read all story files |
| Kendo's Armory | Collect all weapons in the campaign |
| RE: Master of Unlocking | Unlock all safes, lockers, strongboxes and pickable locks |
| Survivor | Complete the game on "Standard" or higher |
| Veteran | Complete the game on "Hardcore" or higher |
| Conqueror | Complete the game on "Nightmare" or higher |
| Dominator | Complete the game on "Inferno" |
| Sensational Work! | Complete the game with an S rank |
| Jill Valentine | Complete the game with an S rank on "Inferno" |
| Minimalist | Complete the game without opening the item box |
| I Might Need These Later! | Complete the game using 1 or fewer recovery items |
| Sprinter | Complete the game in under 2 hours |
| Goodbye, Charlie! | Destroy all Charlie dolls |
