| Made Us Whole | 10 | Complete the game on any difficulty |
| Mission Impossible | 50 | Complete the game on Zealot |
| Hard to the Core | 50 | Complete the game on Hard Core |
| Epic Dismemberment | 50 | Dismember 2,500 Necromorph limbs |
| Fully Loaded | 50 | Simultaneously have four fully upgraded weapons |
| Vacuum Cleaner | 30 | Decompress 20 Necromorphs without getting sucked out yourself |
| Fully Outfitted | 30 | Upgrade your RIG and Stasis completely |
| Picking favorites | 30 | Upgrade 1 weapon completely |
| Romper Stomper | 25 | Stomp 10 containers |
| Frozen in Time | 10 | Kill 50 Necromorphs while in Stasis |
| First Aid | 10 | Use Quick Heal ten times |
| …And Stay Down | 10 | Kill 25 crawling enemies with Stomp |
| Think Fast | 15 | Kill 30 Necromorphs with Kinesis objects |
| The Nanny | 10 | Kill 30 Crawlers without detonating them |
| C-Section | 10 | Knock down with Contact Beam Alt-Fire, kill with Primary before it stands |
| Going for Distance | 20 | Impale an enemy and make it fly 17 meters — must stick to a surface |
| Taste of your own Medicine | 20 | TK-impale a live Slasher to a surface using a Slasher's arm |
| It's a Trap! | 20 | Kill 20 enemies with deployed Detonator Mines |
| Necro Flambé | 10 | Kill 50 enemies with the Flamethrower |
| Peek a Boo! | 20 | Kill a Stalker with the Seeker Rifle in Zoom mode |
| Brute Juke | 10 | Kill a Brute without taking damage |
| Shoot the Limbs! | 10 | Dismember 25 Necromorph limbs |
| Bouncing Betty | 10 | Kill a Cyst by catching and throwing back its mine |
| Skewered in Space | 15 | Impale an enemy into a decompression window to blow it out |
| Clean Cut | 10 | Sever all three tentacles of a Lurker with one Line Gun Primary shot |
| Lawnmower Man | 10 | Kill 4 enemies with the same Ripper blade |
| The Sampler Platter | 20 | Kill a Necromorph with every weapon in the game |
| Lightspeed de Milo | 10 | Dismember the Lightspeed Boy statue |
| Looking good | 10 | Purchase the Advanced Suit |
| The Engineer | 10 | Collect 10 schematics |
| My Boom Stick | 20 | Kill 6 enemies at once with Line Gun's Alt-Fire |
| Shock Therapy | 10 | Impale with the Javelin Gun and shock 3 others with Alt-Fire |
| Collect Peng | 20 | Find the Peng treasure |
| The Librarian | 10 | Collect 100 logs |
| The Electrician | 10 | Collect 10 semiconductors |
